Agap2 Gene Detail Summary Symbol. Agap2 Name. ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. Synonyms. Centg1, PIKE-A, PIKE-L Feature Type

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Max rank score in all spec NCBI Description of AGAP2: The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Human Gene AGAP2 (uc001spq.3) Description and Page Index Description: Homo sapiens ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (AGAP2), transcript variant 1, mRNA. RefSeq Summary (NM_001122772): The protein encoded by this gene belongs to the centaurin gamma-like family. Gene: AGAP2 OTTHUMG00000170285.

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Gene information about ENSG00000135439 / AGAP2 - ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 100130776 - Gene ResultAGAP2-AS1 AGAP2 antisense RNA 1 [ (human)] AGAP2-AS1 AGAP2 antisense RNA 1 [ (human)] AGAP2-AS1 is a prognostic biomarker for patients with GBM, and functions as an oncogenic lncRNA to modulate GBM cell proliferation, apoptosis, migration, and invasion, which suggests that AGAP2-AS1 is potential therapeutic target for GBM. agap2 – vi är en europeisk konsult- och ingenjörskoncern som erbjuder specialistkunskap inom flera industrier. Koncernen stöttar kunder genom att hjälpa dem att genomföra projekt för att leda företagen mot tillväxt. Vi erbjuder expertis och hög kompetens inom alla områden vi är verksamma. cell lines with AGAP2 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. CTD Gene-Chemical Interactions chemicals interacting with AGAP2 gene/protein from the curated CTD Gene-Chemical Interactions dataset. CTD Gene-Disease Associations COSMIC gene AGAP2_ENST00000257897 (COSG2758) Genomic coordinates 12:57723761..57742157 (negative strand) Synonyms AGAP2, CENTG1, CCDS8951.1, Q99490, ENSG00000135439.11, NM_014770.3, NP_055585 COSMIC-3D Couldn't retrieve COSMIC-3D data at this time Number of samples 38743 unique samples 671 unique samples with mutations AGAP2 (Arf GAP with GTP-binding protein-like domain, Ankyrin repeat and PH domain 2) isoform 2 is considered a proto-oncogene, but not much is known about AGAP2 gene expression regulation. To get some insight into this process, AGAP2 proximal promoter was cloned and characterised using reporter assa … Summaries for AGAP2 gene (According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL) About This Sectio Gene symbol: AGAP2: Gene name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2: Chromosome: 12: Chromosomal band: q13.2: Imprinted: Unknown: Genomic reference: NG_029755.1: Transcript reference: NM_014770.3: Associated with diseases-Citation reference(s)-Curators (1) Global Variome, with Curator vacancy: Total number of public Human (116986) Summary: The protein encoded by this gene belongs to the centaurin gamma-like family.

We constructed a 6-gene signature (IQCE, RFX6, GPAA1, BAHCC1, CLEC2B, and AGAP2) as a novel prognostic marker for predicting the survival of melanoma 

Functional Associations. AGAP2-AS1 has 521 functional associations with biological entities spanning 3 categories (chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 15 datasets. AGAP2 was described in two independent studies as a centaurin gamma 1 protein, encoded by CENTG1 gene [13,15,18]. Investigations showed that there are two human gene isoforms for AGAP2: AGAP2 isoform 1 which encodes for PI 3-Kinase Enhancer longer isoform L (PIKE-L), AGAP2 is a protein member of the centaurin gamma-like family.There are two isoforms, 1 and 2, with an antisense long non-coding RNA,

Our lab has been studying AGAP2 gene expression regulation and, as part of this study, we have concentrated in AGAP2 mRNA 5’UTR, finding differences in the length of this UTR in different cell

To get some insight into this process, AGAP2 proximal promoter was … Your search resulted in multiple matches. Please select a position: UCSC Genes AGAP2-AS1 (uc001sps.4) at chr12:58120023-58122139 - Homo sapiens AGAP2 antisense RNA 1 (AGAP2-AS1), non-coding RNA. AGAP2 (uc001spq.3) at chr12:58118076-58132029 - Homo sapiens ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (AGAP2), transcript variant 1, mRNA. AGAP2 (uc001spr.3) at … Protein attributes for AGAP2 Gene Isoform 1 interacts with EPB41L1, PLCG1, NF2, HOMER1 and HOMER2 (By similarity). Isoform 2 interacts with activated AKT1 Sequence=BAA11484.2; Type=Erroneous initiation; Evidence= {ECO:0000305}; Based on the discovery of multiple de novo missense variants in ASD cases, a z-score >2.0 for missense mutations, and a higher-than expected mutation rate (a false discovery rate 15%), AGAP2 was determined to be an ASD candidate gene in Yuen et al., 2017. The gene view histogram is a graphical view of mutations across AGAP2. These mutations are displayed at the amino acid level across the full length of the gene by default.

CTD Gene-Disease Associations COSMIC gene AGAP2_ENST00000257897 (COSG2758) Genomic coordinates 12:57723761..57742157 (negative strand) Synonyms AGAP2, CENTG1, CCDS8951.1, Q99490, ENSG00000135439.11, NM_014770.3, NP_055585 COSMIC-3D Couldn't retrieve COSMIC-3D data at this time Number of samples 38743 unique samples 671 unique samples with mutations AGAP2 (Arf GAP with GTP-binding protein-like domain, Ankyrin repeat and PH domain 2) isoform 2 is considered a proto-oncogene, but not much is known about AGAP2 gene expression regulation. To get some insight into this process, AGAP2 proximal promoter was cloned and characterised using reporter assa … Summaries for AGAP2 gene (According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL) About This Sectio Gene symbol: AGAP2: Gene name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2: Chromosome: 12: Chromosomal band: q13.2: Imprinted: Unknown: Genomic reference: NG_029755.1: Transcript reference: NM_014770.3: Associated with diseases-Citation reference(s)-Curators (1) Global Variome, with Curator vacancy: Total number of public Human (116986) Summary: The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Agap2 MGI Mouse Gene Detail - MGI:3580016 - ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.
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AGAP2 (Arf GAP with GTP-binding protein-like domain, Ankyrin repeat and PH domain 2) isoform 2 is considered a proto-oncogene, but not much is known about AGAP2 gene expression regulation. To get some insight into this process, AGAP2 proximal promoter was cloned and characterised using reporter assays. Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition.

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Gene. Agap2. Species Mouse Transcripts. 2 RefSeqs (NM) Transcript Type Coding Product Type Silencer® Select Availability. Made to Order. Catalog # 4390771 Standard | 5 nmol : …

Quantitative real-time polymerase chain reaction was used to validate AGAP2-AS1 expression in the GC tissues/cell lines compared with that in the adjacent nontumorous tissues/normal epithelial cells. The AGAP2-PGC Fusion FISH Probe is used to confirm a fusion of the AGAP2 and PGC genes. The fusion of the AGAP2 and PGC genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. AGAP2 (Arf GAP with GTP-binding protein-like domain, Ankyrin repeat and PH domain 2) isoform 2 is considered a proto-oncogene, but not much is known about AGAP2 gene expression regulation.

Endocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell 

Jérôme M. Rousseau - Responsable de département - agap2 . AGAP2 Gene - GeneCards | AGAP2 Protein | AGAP2 Antibody. AGAP2  AGAP2 (även känd som CENTG1 eller PIKE ) är en proliferationsaktivator som Significantly mutated genes and related pathways were tested for skewing of  hade fem eller flera DMP ( ESR1, TSPAN4, GARS, MYO1F, SOX18 och AGAP2 ). Vi utförde en GO-analys med DMP-målen med Gene Ontology Database  AGAP2 (ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 2) is a Protein Coding gene. Diseases associated with AGAP2 include Spinal Canal Intradural Extramedullary Neoplasm and Fragile X Syndrome.

agap2 Sweden. Stockholm  AGAP2-AS1 100130776 AGAP2 antisense RNA 112. 58120023 sig. ARVCF. 421 armadillo repeat gene deleted in. 22 54766 B-cell translocation gene 411.